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KMID : 1134820090380010009
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Journal of the Korean Society of Food Science and Nutrition
2009 Volume.38 No. 1 p.9 ~ p.13
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Biological Activities in the Extract of Flos Sophora japonica L.
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Park Sung-Jin
Shin Eon-Hwan
Ham Tae-Sick
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Abstract
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Flos Sophora japonica L. (Leguminosae), commonly called scholar tree, is a well-known traditional medicine used for the treatment of bleeding and as an antihemorrhagic agent. This research was conducted to determine biofunctional activities of Flos Sophora japonica extract. Methanolic extract from Flos Sophora japonica was partitioned by using organic solvents, including n-hexane, ethyl acetate, n-butanol, and water. Ethyl acetate soluble fraction showed the strongest antioxidant activity (RC50=3.13 μg/mL) among the fractions. In antimicrobial activity assays, ethyl acetate soluble fraction was effective to bacterial inhibition, such as Escherichia coli and Klebsiella pneumonia, with minimum inhibitory concentrations in 125 μg/mL. In anticomplementary activity assays, water soluble fraction was the most effective exhibiting 21% inhibitory activity.
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KEYWORD
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Flos Sophora japonica, anticomplement activity, DPPH free radical scavenging activity
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